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Lorazepam enhances the permeability of neuronal membranes to Cl-ions by binding to stereospecific benzodiazepine receptors on postsynaptic GABA neurons. This amplifies the GABA inhibitory activities that result in hyperpolarization and stabilization. A common medication used to treat anxiety disorders, seizures, and sleeplessness is ativan, sometimes known as lorazepam.
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